This weekend, Brighton travel to high-flying Sheffield United, while the likes of Manchester United and Wolves look to secure three points at home against significantly weaker opponents. Here's our mini-preview ahead of the action.
1. Wolves v Norwich City
The Canaries are also in real danger of going down, but their boss Daniel Farke is talking tough ahead of the Wolves game. He's claimed that there's no chance his side are raising a white flag any time soon.
2. Southampton v Aston Villa
The Villains are desperate to escape the relegation scrap, and Dean Smith has been handed a huge boost to help side's efforts, with star John McGinn on the brink of returning from injury. He won't be back this weekend, though.
3. Burnley v Bournemouth
With Man City banned from European competitions for two years, there's an extra place up for grabs. Clarets boss Sean Dyche has said they won't secure it without consistency, ahead of their clash against the Cherries.
4. Liverpool v West Ham
The Reds will look to take another step closer to the title this weekend. Meanwhile, they're said to be stepping up their efforts to land Brazilain wonderkid forward Talles Magno, who plays for Vasco da Gama.